Maria de Fátima Viana Vasco Aragão
1
;
Matheus Barros de Albuquerque
2
;
Mariana Mossi Marques
2
;
Mariana de Carvalho Leal
3
;
Marcelo Moraes Valença
1
;
Danilo Santana Marques
2
;
Letícia Cazuza Nascimento
4
;
Mirelle Maria Palmeira Medeiros Leite de Lima
4
;
Luiz Eduardo Duarte Borges Nunes
2
;
Pedro Henrique Pereira de Andrade
2
;
Pedro César Borba
2
;
Virgílio Sátyro da Nóbrega Segundo
2
;
Lucas Vasco Aragão
5
;
João Pedro Vasco Aragao
6
;
Maria Lúcia Soares
7
;
Gilson Jose Allain Teixeira Junior
8
;
João Eduardo Freire da Fonte
4
;
Francisco Aristofanes Coelho Sarmento Neto
4
1 - Postgraduate Department of Neuropsychiatry and Behavioral Sciences, Universidade Federal de Pernambuco.
2 - Medicine Course, Universidade Federal de Pernambuco.
3 - Department of Surgery, Universidade Federal de Pernambuco.
4 - Department of Radiology, Real Hospital Português de Beneficência em Pernambuco, Recife.
5 - Department of Endoscopy, Hospital Nove de Julho, São Paulo.
6 - Faculdade de Medicina de Olinda.
7 - Universidade Federal de Alagoas.
8 - Department of Tropical Medicine, Universidade Federal de Pernambuco.
Introducción:
Large-scale vaccination against SARS-CoV2 has been modifying the severity profile related to virus infection.
Objetivo:
The goal was to compare clinical profile and radiological findings of the completely COVID-19 vaccinated, the partially vaccinated and the non-vaccinated patients’ groups who had all contracted the COVID-19 disease and needed to undergo radiological exams.
Material y Métodos:
The clinical data of 340 COVID-19 patients were retrospectively reviewed. Of the 340 patients, 208 had information on their vaccination status, laboratory confirmation of COVID-19 and were included in the study. These patients were divided into three groups: i) Completely Vaccinated n=11; ii) Partially Vaccinated n=9 and iii) Non-Vaccinated n= 188. 9 out of 208 patients underwent brain scans. Almost all of these patients were 8/9 (88.9%) from non-vaccinated group.
Resultado:
The radiological findings of the non-vaccinated group brain scans were: 37.5% normal; 12.5% with sequelae from previous vascular injury; 12.5% with subgalea haematoma; 25% with lesions suggesting acute brain microbleeding and microinfarcts; and 12.5% with olfactory mucosae enhancement. The clinical findings from the groups of completely and partially vaccinated patients showed more frequently and with statistical significant difference: diabetes mellitus [6/11 (60%);5/8 (62.5%);22/165 (13.3%) p <0.001F*], systemic arterial hypertension [ 5/8(62.5%); 9/11 (81.8%); 48/166 (28.9%) p <0.001F* ] and dyslipidaemia [ 4/10 (40%); 1/7 (14.3%); 7/163 (4.3%) p <0.001F*].
Conclusiones:
The non-vaccinated patients’ group was more frequent in contracting the COVID-19 disease and in needing to undergo radiological exams on account of their not being protected with vaccination. So, even after the complete vaccination, it will be necessary to maintain social distance, using individual protection equipment, while the virus remains in circulation, mainly to protect the older people with comorbidities.
